Search and Browse
Download
Enter Data
| Solution Information | help | |
| Enzyme: | Nuclear receptor coactivator 2 | |
| inhibitor: | BDBM42974 | |
| substrate: | n/a | |
| Solution Type: | Aqueous | |
| pH at Preparation: | n/a | |
| Temp. Prep.: | n/a | |
| Comments: | Assay Overview: The purpose of this assay is to determine dose response curves for compounds identified as active in a previous set of experiments entitled, "Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)" (PubChem AID 1032). Additionally, compounds selected for testing in this AID were not active or exhibited at least a 3-fold lower % Activation value (compared to AID 1032) in a set of experiments entitled, "Primary biochemical high throughput screening assay to identify agonists of the steroid receptor coactivator 1 (SRC-1) recruitment by PPARgamma," (PubChem AID 631) and "Primary biochemical high throughput screening assay to identify agonists of the steroid receptor coactivator 3 (SRC-3) recruitment by PPARgamma" (PubChem AID 731). This assay tests the ability of test compounds to increase interactions between PPARg and its coactivator | |
| If you find an error in this entry please send us an E-mail | ||
|
Home |
| |
Search |
| |
Deposit |
| |
SiteMap |
| |
About us |
| |
Email us |
| |
Info |
|
©2000 BindingDB. All rights reserved. |
|||||||||||||